Plain-English translation of NCT06991296 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing SPM Active®, an omega-3 supplement designed to reduce chronic inflammation in the body. Researchers want to see if taking this medication daily for 3 months increases special anti-inflammatory compounds in your blood, and whether it also helps with burnout, life satisfaction, and sleep quality.
Obesity is linked to chronic, low-grade inflammation in the body, which can affect overall health and well-being. This study explores whether this medication might help reduce that inflammation and improve quality of life in people with obesity.
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You will take two soft-gel capsules of the medication by mouth each day for 12 weeks. Before you start and after you finish, you'll have a fasting blood test (after not eating for 12 hours) at the University of North Carolina's research lab in Kannapolis, and you'll complete brief surveys about your mood, life satisfaction, and sleep. The entire study takes about 3 months.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States
Sponsor
University of North Carolina, Chapel Hill
Collaborators
Metagenics, Inc.
Enrollment target
~33 participants
Started
June 2025
Primary completion
December 2026
Age range
45 Years – 60 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Saame R Shaikh, PhD
University of North Carolina, Chapel Hill
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.