Plain-English translation of NCT07000045 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two strategies for treating calcium buildup in coronary arteries—the blood vessels that feed your heart. Some patients will receive rotational atherectomy (a mechanical grinding tool) followed by shockwave lithotripsy (sound waves that break apart calcium), while others will receive only the shockwave treatment. Both groups will then have a stent placed to keep the artery open.
Calcium buildup in heart arteries is difficult to treat and can make stent placement less effective. Doctors want to know whether combining two calcium-removal techniques works better than using one technique alone, and which approach gives the best long-term results.
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You will be randomly assigned to receive either the combined treatment (rotational atherectomy plus shockwave lithotripsy) or shockwave lithotripsy alone to prepare your artery. Your doctor will then place a stent. After the procedure, your artery will be imaged with a special camera to see how well the stent fits, and you will be monitored to ensure the stent is working properly. You will need to take blood-thinning medications afterward as prescribed.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
United States