Testing a new injection for emotional distress from serious illness

This study is testing whether RE104, given as a single injection under the skin, can help reduce depression and anxiety in people dealing with serious medical conditions like cancer, ALS, multiple sclerosis, Parkinson's disease, or pulmonary fibrosis. The researchers want to see if this medication works better than a placebo (a dummy injection that looks real but has no active medicine). You would receive either a low dose or a higher dose of the medication, and researchers would track how you feel over time.

When people are diagnosed with or managing serious illnesses, it's common to develop depression and anxiety—a condition called adjustment disorder. Current treatments don't work for everyone, and this trial is exploring whether this new medication could offer another option for people struggling emotionally with their medical diagnosis.