Plain-English translation of NCT07003113 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called ischemic preconditioning—a procedure that safely restricts blood flow to your thigh for short periods. Researchers believe this approach may help reduce pain and improve movement in people with knee osteoarthritis and chronic low back pain. The treatment is done every other day for two weeks.
Knee osteoarthritis and chronic low back pain are very common, especially as we age, and many people struggle to find relief that works. This new treatment may offer another option to help people move more easily and live with less pain.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will receive the blood flow restriction treatment every other day for 2 weeks. Each treatment session lasts 50 minutes and involves placing a cuff on your thigh that restricts blood flow in 5-minute cycles (5 minutes restricted, then 5 minutes of normal flow, repeated). You will be randomly assigned to either receive the active treatment or a sham (placebo) treatment so researchers can see if the real treatment works better.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
United States
University of Illinois at Chicago
Collaborators
National Institute on Disability, Independent Living, and Rehabilitation Research
Enrollment target
~24 participants
Started
September 2025
Primary completion
July 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
50 Years and older
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Shraddha Sudhir
University of Illinois at Chicago
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.