Plain-English translation of NCT07003399 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study looks at how your diaphragm—the main muscle you use to breathe—works differently in people with obstructive sleep apnea (a condition where breathing stops during sleep), chronic obstructive pulmonary disease or COPD (a condition that damages the lungs), or both conditions together. Researchers will use ultrasound imaging and special sensors to measure your breathing muscle strength and how hard your body is working to breathe, then compare results across healthy volunteers and people with these conditions.
Doctors know that sleep apnea and COPD both affect how people breathe, but they don't fully understand how these diseases damage the breathing muscle itself or how to tell if someone has both conditions. This study aims to find objective, measurable signs of breathing muscle damage that could help doctors diagnose and treat these diseases more effectively.
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You will visit the study center for a single session where you'll have an overnight sleep study (polysomnography), breathing tests including spirometry and impulse oscillometry, and ultrasound imaging of your diaphragm combined with surface sensors that measure the electrical activity of your breathing muscle. The study compares these measurements across four groups—healthy people, those with sleep apnea only, those with lung disease only, and those with both conditions—to understand how these diseases affect breathing muscle function.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
China
Sponsor
Nanjing Medical University
Enrollment target
~80 participants
Started
January 2025
Primary completion
August 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ding Ning, doctor
Nanjing Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.