Testing a device to measure toe strength in nerve damage from cancer treatment

Plain-English translation of NCT07009717 on ClinicalTrials.gov ↗ · Source last updated February 2026 · Translation generated June 2026 · How we translate trials

What is this trial?

This study is testing a new portable device called ToeScale that measures the strength of your great toe (big toe). Researchers want to see if this device is accurate and reliable for detecting nerve damage from cancer chemotherapy, and whether it's easy for patients to use.

Nerve damage from chemotherapy is very common in cancer patients, and weakness in the big toe is often one of the first signs. Current methods to measure toe strength are expensive, hard to access, or not very accurate, so researchers developed this new portable device to fill that gap.

Do you qualify?

You likely qualify if…

you are at least 18 years old and able to move your big toe up and down on your own
you can read, understand, and answer questions in English independently
you have been diagnosed with nerve damage from chemotherapy within the last 3 to 6 months, confirmed by a nerve conduction test
you have normal or corrected vision (with glasses or contacts)

You likely don't qualify if…

you have other health conditions like diabetes, arthritis, high blood pressure, thyroid disease, or heart disease that affect nerve function
you have toe deformities or structural problems (such as bunions, hammertoes, or bent toes) not caused by your chemotherapy
you have previous injuries, surgeries, or medical problems that have weakened your foot, ankle, or big toe strength

What participation looks like

If you qualify, you will use the ToeScale device to measure your big toe strength, and answer questionnaires about your symptoms and how the device felt to use. The study compares people with chemotherapy-related nerve damage to healthy adults matched by age and gender, so researchers can understand how the device performs in both groups. The exact number of visits and timeline will be determined during enrollment, but the main activities involve strength testing and survey completion.

AI-generated summary from trial data · Jun 4, 2026 · Not medical advice

Trial locations(1 site)

United States

University of Florida, Gainesville, Florida