Plain-English translation of NCT07010445 on ClinicalTrials.gov β Β· Source last updated Β· Translation generated Β· How we translate trials
This study doesn't follow the usual testing phases β it may be an observational study or a different type of research.
Researchers are investigating whether the bacteria living in your gut play a role in epilepsy and how they may be affected by seizure medications or epilepsy treatments. This study will follow people newly diagnosed with seizures and people with drug-resistant epilepsy (seizures that don't respond well to medication) for up to one year, collecting information about their symptoms, gut bacteria, and response to different treatments like surgery, vagus nerve stimulation, or ketogenic diet therapy.
Scientists have noticed a strong connection between gut bacteria and epilepsy, but don't yet understand whether unhealthy gut bacteria trigger seizures, or whether seizure medications change the bacteria. This study aims to clarify that relationship so doctors can eventually develop better treatments based on gut health.
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You will visit the clinic as an outpatient or inpatient at four time points over about 15 months: at enrollment, then at 1 month, 6 months, and 12 months after starting treatment. At each visit, you'll have a physical exam, blood work, and provide stool samples to analyze your gut bacteria. Depending on your group, you may also have brain scans, seizure monitoring, and keep a seizure diary to help researchers track how your condition changes.
AI-generated summary from trial data Β· Jun 1, 2026 Β· Not medical advice
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