Plain-English translation of NCT07012993 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new way to perform brain imaging scans that detect signs of Alzheimer's disease and other memory disorders. Researchers are using 18F-Florbetapir and 18F-Flutemetamol—chemicals that naturally collect in areas of the brain affected by these conditions—but at much smaller doses than are normally used. The goal is to create clear images while exposing you to 10 to 100 times less radiation than traditional scans.
Standard brain imaging for memory problems requires fairly high doses of radiation, which can limit how often patients can safely be scanned. This research aims to develop a safer imaging technique that could be used more frequently for screening and monitoring Alzheimer's disease and other forms of dementia without putting patients at unnecessary risk.
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You will receive a small injection of a radioactive tracer—a tiny amount designed to show how the imaging works at very low doses. You will then lie in a PET scanner for up to 3 hours while the machine takes pictures of your brain. The entire process is non-invasive and painless, though you will need to remain still during the scan.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States