Plain-English translation of NCT07013929 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hypertension research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The Spyral InSight study is testing a new approach to treating high blood pressure using the Symplicity Spyral system. This procedure involves renal nerve stimulation—a technique that works on the nerves in your kidneys—performed both before and after a renal artery denervation treatment. Researchers want to understand how safe this combined approach is and how your body responds to it.
High blood pressure affects millions of people, and some patients don't get enough relief from medications alone. This trial is exploring whether this new nerve-stimulation technique could offer an additional treatment option for people whose blood pressure remains difficult to control.
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You would undergo a minimally invasive procedure in which doctors use the Symplicity Spyral system to perform nerve stimulation before and after renal artery denervation. After the procedure, you'll have follow-up visits at 1, 3, 6, and 12 months so the research team can monitor your safety, blood pressure response, and how your body reacts to the treatment. The study involves standard blood pressure checks and assessments at each visit.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Greece
Ireland
Sponsor
Medtronic Vascular
Enrollment target
~19 participants
Started
June 2025
Primary completion
February 2027
Age range
20 Years – 70 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sjors Wijnands
Medtronic Vascular
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.