Recruiting

Testing a Skin Cream for Eczema in Babies, Children, and Adults

Plain-English translation of NCT07014007 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated June 2026 · How we translate trials

Read our Atopic Dermatitis research guide →

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a medicated cream called RV4421B-EV0407 that is already sold in several countries for treating eczema, including atopic dermatitis. Researchers want to understand how safe and effective this medication is when used alone or combined with steroid creams, especially in people with different skin tones and across different age groups. The study will follow participants for 12 weeks with regular check-ins to measure how well the treatment works.

While this treatment is already available in some countries, doctors and patients need more research to understand how well and safely the medication works in diverse populations—including babies, children, teenagers, and adults with different skin types—when used over a longer period of time.

Do you qualify?

You likely qualify if…

you are between 3 months and 23 months old (infants), 24 months and 12 years old (children), or 13 years and older (teenagers and adults)
you have been diagnosed with mild to moderate atopic dermatitis using established medical criteria
your eczema affects no more than 30% of your body's surface area
you have any skin tone or ethnicity—the study specifically welcomes people with all skin types
you have been using topical corticosteroid cream for 1 to 5 days before joining and are currently using it

You likely don't qualify if…

you have allergies or sensitivities to any ingredients in the study cream or materials used in the research
you have other skin conditions besides atopic dermatitis, or tattoos or marks on the areas being studied that could interfere with assessment
you are currently taking or have recently started systemic medications (by mouth or injection) like immune-suppressing drugs, oral steroids, oral antibiotics for skin conditions, or antihistamines within 2–12 weeks before joining
you have received light therapy (phototherapy) for your skin within 4 weeks before the study or plan to start it during the study
for infants and young children: your eczema is located in the diaper area

What participation looks like

You would apply the medicated cream to your eczema twice daily for 12 weeks, either on its own or alongside your regular steroid cream. You'll attend 5 visits over this time: an initial visit on Day 1, a phone check-in between Days 8–15, and three in-person visits around Days 29, 57, and 85. At each visit, doctors will examine your skin and ask how well the treatment is working and whether you're experiencing any side effects.

AI-generated summary from trial data · Jun 6, 2026 · Not medical advice

Testing a Skin Cream for Eczema in Babies, Children, and Adults

What is this trial?

Do you qualify?

What participation looks like

Trial locations