Plain-English translation of NCT07020026 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson's Disease research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers are using a special brain imaging scan called PET to look for tau protein buildup in the brains of people with Parkinson's disease. This study compares tau levels in people with different types of Parkinson's disease, people with related neurological conditions, and healthy volunteers. The goal is to better understand how tau protein relates to Parkinson's disease and whether it could help doctors diagnose or track the disease.
Scientists know that tau protein buildup is linked to several brain diseases, but they don't fully understand its role in Parkinson's disease yet. This imaging study could help doctors identify tau-related brain changes in Parkinson's patients and potentially lead to better ways to diagnose and monitor the disease.
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You will have brain imaging scans using a special PET camera that takes pictures of tau protein in your brain. If you join in the first year, you may have scans on two different types of PET cameras so researchers can compare them. Most participants will have a follow-up scan one year after their first scan. The study takes place over two years, and many visits will use data already collected from another research study to reduce the burden on you.
AI-generated summary from trial data · Aug 16, 2026 · Not medical advice
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