Plain-English translation of NCT07026461 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing two different approaches to brain stimulation for people with depression. One approach uses right-sided repetitive transcranial magnetic stimulation (rTMS), while the other uses left-sided intermittent theta burst stimulation (iTBS). Both are non-invasive techniques that use magnetic pulses to stimulate specific areas of the brain, and researchers want to know if they work equally well.
Depression can be difficult to treat, and not all medications work for everyone. Brain stimulation is an option for people who haven't responded well to other treatments, but doctors want to understand which stimulation approach is most effective and easiest for patients to tolerate.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive one of two types of brain stimulation: either right-sided 1-Hz stimulation or left-sided intermittent theta burst stimulation. Throughout the treatment period, you'll have regular appointments where your depression symptoms will be measured using rating scales and questionnaires. Researchers will also track any side effects, your overall quality of life, and whether the treatment helps reduce your depression.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Sweden
Phase
Post-approval monitoring
Sponsor
Region Örebro County
Collaborators
Uppsala County Council, Sweden
Enrollment target
~350 participants
Started
December 2025
Primary completion
December 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Axel Nordenskjöld, MD,PhD
Region Örebro County, Örebro University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.