Plain-English translation of NCT07029152 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Anal Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is evaluating the best ways to screen for early warning signs of anal cancer in men who have sex with men (MSM) who are using Pre-Exposure Prophylaxis (PrEP) — a medication that helps prevent HIV infection. Researchers want to understand how common these early warning signs are, how accurate different screening methods are at finding them, and how screening affects quality of life. The study will also test a new approach using DNA analysis to better identify who might be at higher risk.
Men who have sex with men have a higher risk of developing anal cancer compared to other groups. Currently, there aren't clear guidelines about the best way to screen for this disease early, when it's most treatable. This study aims to fill that gap by finding the most effective screening strategies for people taking this medication.
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If you join this study, you will complete health and quality of life questionnaires, have an anal swab sample collected, and undergo a detailed visual examination of the anal area using a special magnifying instrument called high-resolution anoscopy. These procedures help researchers look for early warning signs of anal cancer and test new detection methods. The study takes place at one of several research centers in Europe.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
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