Plain-English translation of NCT07033156 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is exploring a new way to screen for colorectal cancer using DNA methylation technology — a method that looks at chemical changes in DNA found in stool samples. Instead of undergoing invasive procedures, participants would simply provide a stool sample that researchers analyze to see if this non-invasive approach can reliably detect colorectal cancer and precancerous growths (called adenomas) in people over 40. The goal is to develop a simple, at-home screening tool that could catch cancer early when it's easier to treat.
Colorectal cancer is a serious disease, but it's often preventable or more treatable when caught early. However, many people avoid screening because existing methods are uncomfortable or invasive. This study aims to solve that problem by creating an easier, non-invasive screening option using stool samples.
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If you qualify, you would provide a stool sample (and possibly a blood sample) within 3 months before you have a colonoscopy — a procedure your doctor may already be recommending as part of routine screening. Your samples would be tested using the new DNA methylation technology to see if it can detect cancer or precancerous changes. Researchers will compare the results from your samples with your colonoscopy and pathology findings to evaluate how well the test works. The study is for research purposes only and will not affect your actual clinical diagnosis or treatment.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
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