Plain-English translation of NCT07036003 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether Saizen Somatropin, a recombinant human growth hormone (rHGH), can help people with knee osteoarthritis. Researchers want to see if this medication can reduce knee pain and improve how well the knee works. The study will also measure whether people can comfortably stick with self-injecting the treatment every day.
Knee osteoarthritis causes pain and loss of function in many adults, and current treatments don't work well for everyone. This medication may help by supporting tissue repair and reducing inflammation in the knee.
You would come in for an initial visit to have blood tests and measurements taken of your knee strength, range of motion, and walking ability. Then, you would self-inject either the growth hormone or a placebo (salt solution) into your belly or buttocks once per day for 6 weeks. During this time, you'll complete surveys about your pain and daily activities, and return for a follow-up visit where researchers will repeat the measurements and blood tests to see if the treatment helped.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
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