Plain-English translation of NCT07044362 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a combination of two treatments for colorectal cancer that has spread to the liver: histotripsy (a non-invasive procedure that uses sound waves to destroy tumors) plus . The histotripsy procedure has already been approved by the FDA for treating liver tumors. Researchers want to see if adding this treatment to your regular helps people with advanced liver metastases.
Many people with colorectal cancer that has spread to the liver cannot have surgery to remove all the tumors. This trial exists to find out if combining the new sound wave treatment with can better control the cancer and improve outcomes for patients in this difficult situation.
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If you join this trial, you will receive histotripsy treatment (using sound waves to destroy liver tumors) while continuing your regular without interruption. The histotripsy procedure will be performed under general anesthesia. You will work with the research team to coordinate your schedule with the histotripsy treatment and attend follow-up visits to monitor how well the combined treatment is working.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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