Testing brain surgery without steroid medication beforehand

This trial is testing whether it is safe to skip dexamethasone — a steroid medication commonly given before and after brain surgery — in patients with cancer that has spread to the brain. Researchers want to understand whether patients can undergo surgery to remove these brain tumors without this steroid, and whether doing so causes any harm or complications.

Steroids like dexamethasone have been used routinely during brain surgery for many years, but doctors are now asking whether this medication is truly necessary for every patient. By studying whether the treatment can be safely withheld, researchers hope to reduce unnecessary medication exposure and understand which patients actually benefit from receiving it.