Plain-English translation of NCT07045753 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is a long-term registry that tracks patients with severe mitral regurgitation (a condition where the heart's mitral valve leaks blood backward) who receive a minimally invasive repair procedure called transcatheter edge-to-edge repair. Doctors at the Heart Center in Bad Segeberg, Germany, are enrolling up to 2,000 patients to understand how well this treatment works over many years and what happens to patients after the procedure.
While this repair procedure has helped many patients avoid open-heart surgery, doctors need detailed long-term information about how patients fare after treatment—whether the repair holds up, how symptoms improve, and what complications might arise. This registry will help doctors better understand who benefits most from this approach and how to improve care.
You likely qualify if…
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You would receive the standard repair procedure at the Heart Center and then return for regular follow-up visits as part of your normal medical care. The study simply tracks your health information and outcomes over a long period, so you're not undergoing any extra tests or procedures beyond routine care. Your doctors will monitor how well the repair is working and how you're doing.
AI-generated summary from trial data · Aug 12, 2026 · Not medical advice
Germany
Enrollment target
~2,000 participants
Started
January 2011
Primary completion
December 2030
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Arief Kurniadi, MD
Herzzentrum Segeberger Kliniken GmbH
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.