Plain-English translation of NCT07046546 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is the first UK study testing thyroid artery embolization (TAE), a new minimally invasive procedure for people with large, benign thyroid nodules that are causing problems. During the procedure, a doctor inserts a thin tube into an artery and uses tiny particles to block blood flow to the thyroid, which helps shrink the nodule and relieve symptoms like neck tightness or cosmetic concerns. Early research from other countries suggests this treatment is safe and effective, but it has never been studied in the UK, so this trial aims to confirm it works safely here.
Patients with large thyroid nodules currently have limited treatment options—surgery risks permanent scarring and damage, radioactive iodine can cause long-term thyroid problems requiring daily medication, and other procedures don't work well on very large nodules. This treatment could offer patients a safer, less invasive option that causes fewer long-term side effects.
You likely qualify if…
You likely don't qualify if…
You will visit the Royal Berkshire NHS Foundation Trust for an initial assessment with a specialist doctor who confirms your thyroid nodule qualifies for the procedure. On the day of treatment, you will lie on a special imaging table and receive anesthesia while the doctor performs the embolization procedure, which typically takes a few hours. You'll have follow-up visits and imaging scans afterward to monitor how well the treatment worked and check for any side effects.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United Kingdom