Testing a New Minimally Invasive Procedure for Large Thyroid Nodules

This is the first UK study testing thyroid artery embolization (TAE), a new minimally invasive procedure for people with large, benign thyroid nodules that are causing problems. During the procedure, a doctor inserts a thin tube into an artery and uses tiny particles to block blood flow to the thyroid, which helps shrink the nodule and relieve symptoms like neck tightness or cosmetic concerns. Early research from other countries suggests this treatment is safe and effective, but it has never been studied in the UK, so this trial aims to confirm it works safely here.

Patients with large thyroid nodules currently have limited treatment options—surgery risks permanent scarring and damage, radioactive iodine can cause long-term thyroid problems requiring daily medication, and other procedures don't work well on very large nodules. This treatment could offer patients a safer, less invasive option that causes fewer long-term side effects.