Gene therapy delivered through heart catheter for severe chest pain

This study is testing whether XC001, a gene therapy delivered directly into the heart through a thin tube called a catheter, can reduce chest pain in people with severe coronary artery disease. The treatment is designed for patients whose chest pain hasn't gotten better with medications or who aren't candidates for traditional surgery or angioplasty. Researchers want to see if this medication can help the heart create new blood vessels to improve blood flow and relieve pain.

Many patients with severe chest pain have already tried multiple medications and are not able to have traditional heart procedures, leaving them with few options. This medication is being tested as a potential new treatment for these patients who have run out of other choices.