Plain-English translation of NCT07052435 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether two types of measurements — one called Fractional Flow Reserve (FFR) and another called Vascular Flow Reserve — can help doctors make better decisions about treating blocked arteries in your legs. These measurements use a thin, pressure-sensitive wire placed inside your artery during a procedure to show doctors exactly how much blood can flow through the blockage. The goal is to help doctors decide which blockages really need treatment and which ones might not, so you get the right care for your condition.
Currently, doctors often decide whether to treat a blocked artery based mainly on what they see in imaging pictures, but these pictures can be misleading. This trial exists to see whether using pressure and flow measurements can give doctors more objective, accurate information to guide their treatment decisions and help avoid unnecessary procedures.
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If you join this trial, you will undergo a procedure where doctors will use a special pressure-sensitive wire to measure blood flow in your blocked leg artery. During the procedure, they will take pressure readings before and after the blockage to help decide whether intervention like balloon angioplasty or a stent is needed. The trial is collecting data from about 100 people to see how these measurements help improve treatment decisions.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
Greece
Sponsor
Dr. Konstantinos Katsanos
Collaborators
Medlytic Labs, Attikon Hospital
Enrollment target
~100 participants
Started
September 2024
Primary completion
September 2028
Last updated on clinicaltrials.gov in July 2025.
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Central contact
Konstantinos Katsanos, MSc, MD, PhD, EBIR
Dr. Konstantinos Katsanos
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