Plain-English translation of NCT07052539 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why kidney disease and a specific type of heart problem (called HFpEF, where the heart doesn't fill with blood properly) often happen together in people with obesity. This study will compare how three groups of people handle salt and protein in their bodies: healthy people, people with obesity, and people with both obesity and this heart condition. By studying these differences, doctors hope to find better ways to diagnose and treat these conditions.
Many people with obesity develop both kidney disease and this type of heart failure at the same time, but doctors don't fully understand why or how to best evaluate these patients. This research aims to fill that gap and improve care.
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You will visit the research center where doctors will perform tests to measure how your kidneys handle salt and protein, likely including blood tests, urine tests, and possibly imaging scans. The study compares three different groups (healthy volunteers, people with obesity, and people with both obesity and heart problems), so your specific visits and tests will depend on which group you join. The entire process is designed to gather information that helps researchers understand the connection between these conditions.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Sponsor
University of Mississippi Medical Center
Enrollment target
~60 participants
Started
July 2022
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in July 2025.
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Central contact
Tekka Johnson
University of Mississippi Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.