Plain-English translation of NCT07052799 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether aspirin — a blood-thinning medication many heart patients take daily — should be continued or stopped when someone needs a colonoscopy for colon cancer screening. Researchers want to know if keeping patients on aspirin during this procedure better protects their heart, or if stopping it reduces bleeding risk without harming cardiovascular health.
Right now, doctors disagree about whether patients should keep taking this medication before and after a colonoscopy. Some worry it causes too much bleeding, while others believe stopping it puts the heart at risk. This study will provide clear evidence to guide the safest approach for patients with moderate cardiovascular risk.
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You would receive either aspirin or a placebo pill to take for 8 days (5 days before your colonoscopy through 3 days after). You'll undergo a standard colonoscopy as planned, and researchers will track whether you experience any bleeding complications or heart problems over the following weeks. The study involves about 2,514 patients total, and your participation helps determine the safest aspirin management strategy for future patients.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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