Plain-English translation of NCT07053254 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying tissue samples collected during heart bypass surgery in older adults with coronary artery disease. The study uses advanced laboratory techniques to analyze how blood vessel grafts—the vessels used to bypass blocked arteries—develop and work in elderly patients. This research could help doctors improve bypass surgery outcomes and better understand vascular health in aging.
Coronary artery disease affects millions of older adults, and bypass surgery is a common treatment. However, doctors don't fully understand how blood vessel grafts change and age in elderly patients, or why they sometimes develop problems over time. This research aims to fill that knowledge gap so future treatments can be more effective.
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If you qualify and choose to participate, researchers will collect small pieces of blood vessel graft tissue that would otherwise be discarded during your bypass surgery—so there is no extra surgery or risk to you. The tissue samples are then analyzed in the laboratory using advanced molecular techniques to understand how the grafts function. Your participation ends after the tissue is collected; there are no follow-up visits or additional procedures required.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
South Korea
Sponsor
Yonsei University
Enrollment target
~100 participants
Started
April 2022
Primary completion
April 2027
Age range
19 Years – 100 Years
Last updated on clinicaltrials.gov in July 2025.
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