Plain-English translation of NCT07053475 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether —an iron treatment given by IV injection—works better than oral iron pills for people with heart failure and iron deficiency. Researchers want to know if the injection helps you walk farther, feel better, and have fewer symptoms than taking iron pills over 24 weeks.
Many people with heart failure also have low iron, which can make their symptoms worse and reduce how much they can exercise. Doctors are not sure whether giving iron through an injection or as pills works better, so this study will help them decide which approach is safer and more effective.
You will be randomly assigned to receive either IV iron injections or daily iron pills for 24 weeks. If you receive the injection, you will get one infusion at the start and possibly a second one at week 6 at the clinic. If you take pills, you will take them twice daily at home. You will visit the clinic at 6 weeks and 12 weeks for blood tests, a walking test, and questionnaires about your symptoms and quality of life.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States