Plain-English translation of NCT07055152 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand a condition called MINOCA—where people have a heart attack but their coronary arteries aren't blocked. This study uses a special eye imaging technique (OCTA) to look at the tiny blood vessels in your retina, because changes there may reflect what's happening in the heart's blood vessels. By comparing eye imaging in three groups—people with MINOCA, people with typical heart attacks, and healthy people—doctors hope to learn why MINOCA happens and predict who might have better or worse outcomes.
MINOCA is confusing because the heart is damaged but the main arteries look normal on standard tests. Researchers believe tiny blood vessels throughout the body—including in the eyes—may be the real problem. This study could help doctors diagnose MINOCA earlier and predict which patients need more aggressive treatment.
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If you're selected, you'll visit the study center for eye imaging (OCTA scan) and possibly other heart imaging or blood tests, depending on which group you're in. The eye imaging is painless and non-invasive—similar to taking a photograph of the back of your eye. Researchers will compare your eye blood vessel patterns with others in your group to look for differences. The study involves about 90 people total split into three groups, and you may be asked to return for follow-up visits to see how you're doing over time.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
Italy
Sponsor
University of Pisa
Enrollment target
~90 participants
Started
January 2025
Primary completion
January 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Last updated on clinicaltrials.gov in July 2025.
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Central contact
Mattia Alberti, Dr
University of Pisa
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