Plain-English translation of NCT07058805 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial tests a new approach to radiation therapy after surgery for head and neck squamous cell carcinoma. Instead of treating large areas of the neck and head with radiation (the standard approach), this study uses pathology tests and imaging to create a personalized plan that skips radiation in certain areas. The goal is to reduce side effects while still controlling cancer effectively.
Standard radiation therapy after head and neck cancer surgery treats large areas to be safe, but this causes significant side effects like difficulty swallowing, dry mouth, and other problems that affect quality of life. Early research suggests that skipping radiation in selected areas—based on careful analysis of the tumor—may be just as effective while reducing these harmful effects.
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You will receive radiation therapy tailored to your specific tumor characteristics—some areas of your neck and head may be skipped based on your pathology results and imaging. You may also receive chemotherapy or immunotherapy along with radiation, depending on your case. Throughout the study, you will have follow-up visits with your radiation oncologist, complete quality-of-life surveys, and undergo imaging scans. The total commitment is about 30 months of follow-up, with the most frequent visits during and shortly after treatment.
AI-generated summary from trial data · Sep 2, 2026 · Not medical advice
Switzerland