Plain-English translation of NCT07058805 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new approach to radiation therapy for patients who have had surgery for head and neck squamous cell carcinoma. Instead of treating large areas with radiation as standard practice does, this study uses a personalized, compartmentalized approach that treats only the specific areas most likely to need it based on your pathology results and imaging. The goal is to reduce the side effects and impact on quality of life while keeping you safe from cancer recurrence.
Standard radiation therapy after head and neck cancer surgery treats large areas of the neck and throat, which can cause significant side effects like difficulty swallowing, dry mouth, and voice changes. This trial exists to see if treating a smaller, more targeted area based on your individual cancer characteristics can reduce these harmful effects without compromising your cancer care.
You likely qualify if…
You likely don't qualify if…
You will receive personalized radiation therapy designed based on your surgical pathology and imaging results — some areas normally treated may be safely omitted based on a predefined algorithm. You will visit your radiation oncologist within 28 days before starting treatment, undergo the radiation course (typically over several weeks), and then be followed closely for 30 months with imaging scans, blood tests, and questionnaires about side effects and quality of life. You may also receive additional systemic treatment (chemotherapy or immunotherapy) if your medical team determines it is necessary.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
Switzerland