Plain-English translation of NCT07060066 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called transcranial magnetic stimulation (TMS) using a special H-coil device to treat depression in people with schizophrenia. TMS is a non-invasive procedure that uses magnetic pulses to stimulate specific areas of the brain. Thousands of patients with depression have already benefited from TMS, but this is the first study specifically looking at whether this approach can help people who have both schizophrenia and depression.
Many people with schizophrenia also experience depression, which makes their symptoms worse, increases their suicide risk, and leads to worse outcomes and more hospitalizations. Currently, there are no proven treatments specifically designed for this combination, so this trial is testing whether this treatment can safely and effectively reduce depression in this vulnerable group.
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You would visit the clinic for about 4 weeks to receive the magnetic stimulation treatment. During each visit, you would receive three short sessions of brain stimulation with about 30 minutes between sessions, with up to 20 total visits. About half of participants will receive the active treatment, and half will receive a sham (fake) treatment so researchers can see if the real treatment actually works. You may also be asked to complete brain scans and answer questions about your mood and symptoms.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States
Sponsor
The University of Texas Health Science Center, Houston
Collaborators
National Institute of Mental Health (NIMH)
Enrollment target
~120 participants
Started
May 2024
Primary completion
June 2030
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Alina Siatka
The University of Texas Health Science Center, Houston
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.