How Birth Control Pills Affect Blood Pressure Over 24 Hours

Plain-English translation of NCT07061093 on ClinicalTrials.gov ↗ · Source last updated July 2025 · Translation generated June 2026 · How we translate trials

What is this trial?

Researchers want to understand whether newer formulations of hormonal birth control pills — specifically those containing combined with new types of estrogen, or alone — have any effect on your blood pressure and heart rate. This is an observational study, meaning you'll use the medication (or no hormonal contraception) as you normally would, while doctors monitor your cardiovascular health.

Hormonal birth control can sometimes raise blood pressure in some women. This study is investigating whether the newer formulations of this medication have fewer or different effects on blood pressure compared to what we know about older versions, so doctors can make better recommendations for their patients.

Do you qualify?

You likely qualify if…

you are a woman between 18 and 50 years old
you have regular menstrual cycles (between 21 and 35 days)
you are sexually active, want to prevent pregnancy, and are willing to use hormonal birth control for at least 4 months
your body mass index is between 18 and 30
you are in good physical and mental health

You likely don't qualify if…

you have a personal or family history of blood clots, stroke, or heart attack
you have migraine with focal neurological symptoms (aura)
you have diabetes with complications affecting blood vessels
you have high blood pressure (above 140/90 mmHg) or severe cholesterol problems
you have liver disease, liver tumors, or a history of hormone-sensitive cancer

What participation looks like

You will visit the research clinic twice over a 4-month period (at the start and after completing 4 cycles of birth control). At each visit, researchers will measure your height, weight, and blood pressure, and you'll wear a portable blood pressure monitor for 40 hours to track your readings throughout the day and night. Between visits, you'll use your chosen birth control method (or no hormonal contraception) as normal.

AI-generated summary from trial data · Jun 22, 2026 · Not medical advice

Trial locations(1 site)

Italy

Ospedale San Martino, Genova, GE