Cooling therapy to prevent nerve damage from cancer chemotherapy

This trial is testing whether a device called the Paxman Limb Cryocompression System — which cools and gently compresses your arms and legs — can help prevent a common side effect of taxane chemotherapy called peripheral neuropathy. Peripheral neuropathy is nerve damage that causes numbness, tingling, pain, or weakness in your hands and feet. Some early research suggests that cooling therapy may protect nerves during chemotherapy, and this study will see whether this approach really works and is safe.

Many people receiving taxane chemotherapy develop peripheral neuropathy, which can be painful and long-lasting, and there are limited ways to prevent it. This trial exists to find out whether this treatment can reduce that risk and improve quality of life for cancer patients.