Starting breathing support early in ALS patients

This trial is testing whether people with ALS benefit from starting non-invasive ventilation (a breathing support mask) earlier than doctors typically recommend. Non-invasive ventilation is a mask-based therapy that helps your lungs work when ALS weakens your breathing muscles. The study wants to learn whether starting this treatment sooner improves both how long you live and your quality of life.

ALS gradually weakens the muscles you use to breathe, and breathing problems are the main reason people with ALS become seriously ill. While non-invasive ventilation is known to help, doctors aren't sure when to start it—some wait until breathing is very severely affected, while others start earlier. This study will help answer that question and find the best timing for this treatment.