Plain-English translation of NCT07073235 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a treatment called intermittent theta burst stimulation (iTBS)—a non-invasive brain stimulation technique—to see if it can help people who've had a stroke regain better movement and strength in their legs. Half of the participants will receive the real brain stimulation, while the other half will receive a placebo (sham) version, and both groups will also do 45 minutes of physical therapy three times per week for five weeks. Researchers will use brain imaging before and after the treatment to understand how the brain changes and adapts during recovery.
Many people have lasting difficulty moving their legs after a stroke, even months or years later. This trial is exploring whether brain stimulation combined with physical therapy might unlock new pathways in the brain and help improve movement and walking ability beyond what physical therapy alone can achieve.
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You'll visit the hospital or clinic for an initial brain scan and assessment. Then, over 5 weeks, you'll come in 3 times per week for sessions that include either real or placebo brain stimulation (about 3 minutes), followed by 45 minutes of guided physical therapy focused on your legs and walking. At the end, you'll have another brain scan so researchers can see what changed. A physiotherapist will guide your therapy, and you won't know whether you received the real or placebo stimulation until the study is complete.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
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