Plain-English translation of NCT07075731 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at cancer screening for transgender and gender-diverse people who are planning to have gender-affirming hysterectomy surgery. Specifically, researchers want to understand what cancer screening tests are being done before surgery, whether those tests are needed, and what testing options feel comfortable and practical for patients.
There are currently no clear medical guidelines about which cancer screening tests should be done before this surgery for transgender and gender-diverse patients. This study will gather information to help doctors provide better, more personalized care and to develop evidence-based guidelines for the future.
You likely qualify if…
You likely don't qualify if…
You would share information about any cancer screening tests you've had or plan to have before your hysterectomy. Depending on which arm of the study you join, you may complete standard screening tests, try a self-swab cervical cancer screening option, or participate in a practice version of the self-swab test. The study will then compare your screening results with your surgical pathology findings to understand what screening approaches are most helpful.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United States
Enrollment target
~40 participants
Started
June 2025
Primary completion
June 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Samantha Hoffman, MD
University of Minnesota
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.