Plain-English translation of NCT07080567 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
The MASTER trial is testing whether a medication called can help people recover better motor function (movement and strength) after an ischemic stroke. In laboratory studies, this medication has shown promise in reducing brain damage and helping the brain rewire itself to regain lost function. This study will see if those benefits work in real patients.
After a stroke, many people are left with lasting weakness or loss of movement, even after receiving the best emergency treatments available. This medication might help the brain heal and adapt more effectively during the early recovery period, but researchers need to test whether it actually works in patients.
You likely qualify if…
You likely don't qualify if…
If you join, you would take the study medication (or placebo) twice daily for 90 days, starting within a week of your stroke. You'll come for regular clinic visits where researchers will test your arm and hand strength, take brain images, and ask you to perform movement tasks. You'll also be checked at a 6-month follow-up visit after your stroke to see how well you've recovered. Neither you nor the study team will know whether you're receiving the real medication or placebo during the trial.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
Switzerland
Phase
Testing effectiveness
Sponsor
Emmanuel Carrera
Enrollment target
~80 participants
Started
July 2025
Primary completion
December 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Emmanuel Carrera, MD
Hôpitaux Universitaires Genève
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.