Plain-English translation of NCT07082595 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new approach called targeted auditory stimulation during sleep (TASS) for people with Parkinson's disease who have difficulty walking or keeping their balance. Researchers will play specific sounds during your sleep while you're receiving physical rehabilitation, with the goal of helping your brain better remember and retain the walking improvements you learn in therapy. Half of participants will receive the real sound stimulation, and half will receive a sham (fake) version, so researchers can see if the sounds actually make a difference.
People with Parkinson's disease often struggle with walking and balance, and while rehabilitation therapy can help, the improvements don't work the same way for everyone. This trial exists to test whether this new treatment can boost the benefits of rehabilitation by helping your brain lock in the movement patterns you learn during therapy.
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You will attend rehabilitation sessions as planned while also wearing a special headband or electrode that plays sounds during your sleep on certain nights. Some nights you'll receive the real targeted sounds designed to reinforce what you learned in therapy, and other nights you'll receive fake sounds (you won't know which is which). Researchers will measure your walking ability and balance at the start, during, and at the end of the study to see if the sound stimulation helped you improve more than the control group. The study involves about 40 people total and takes place at the University of Zurich.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
Switzerland