Plain-English translation of NCT07083011 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing a new imaging scan called 68Ga-FAPI PET to help doctors better understand and diagnose heart failure with preserved ejection fraction (HFpEF)—a condition where the heart doesn't relax properly between beats, even though its pumping strength is normal. The scan uses a small amount of radioactive tracer to highlight areas of scarring and stiffness in the heart. Researchers want to see if this imaging tool can help identify patients with this type of heart failure more accurately.
Many patients with HFpEF are difficult to diagnose because their hearts look strong on standard tests, yet they still have troubling symptoms like shortness of breath. This trial exists to determine whether the new imaging scan can detect hidden changes in heart tissue that standard tests miss, potentially helping doctors identify and treat this condition earlier.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will visit Mayo Clinic to undergo the new imaging scan along with other standard heart imaging tests to compare results. The scans are non-invasive and performed while you lie flat on a table; the entire visit typically takes a few hours. You'll also be asked about your symptoms and medical history to help the researchers understand how well the new scan works in identifying your condition.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United States
Phase
Testing effectiveness
Sponsor
Mayo Clinic
Enrollment target
~35 participants
Started
November 2025
Primary completion
July 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jake Nemgar
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.