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A Special Diet to Help Type 2 Diabetes and Fatty Liver Disease

Plain-English translation of NCT07083336 on ClinicalTrials.gov ↗ · Source last updated July 2025 · Translation generated June 2026 · How we translate trials

Read our Type 2 Diabetes Mellitus research guide →

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a Chinese Medical Nutrition Therapy (CMNT) diet designed specifically for people who have both type 2 diabetes and a fatty liver. The diet involves eating a prepared meal plan for 5 days, then eating normally for 10 days, and repeating this cycle. Researchers want to see if this approach helps reduce fat in the liver and improves blood sugar control better than standard dietary guidelines.

Many people with type 2 diabetes also develop fatty liver disease, which can lead to serious liver damage over time. This study exists because doctors need better dietary strategies to treat both conditions together, and researchers believe the special meal plan may work better by targeting liver fat specifically.

Do you qualify?

You likely qualify if…

you have been diagnosed with type 2 diabetes and fatty liver disease
you are between 18 and 75 years old
your weight has stayed stable for at least 3 months (no more than 4 kg gain or loss)
you have been on the same diabetes medications (1–3 oral medications, with or without insulin) for at least 3 months, or you are not yet taking diabetes medication
you can provide written consent to participate

You likely don't qualify if…

you have had a heart attack, stroke, or heart surgery in the past 6 months
you have serious liver disease such as cirrhosis or severe hepatitis
you have had cancer in the past 5 years
you are currently taking medications that affect blood sugar (such as steroids) or medications for blood pressure or cholesterol that are not yet at a stable dose
you have had severe low blood sugar episodes (2 or more) in the past 6 months

What participation looks like

If you join this study, you will be assigned to either the new CMNT diet group or a standard dietary advice group. If you are in the diet group, you will eat prepared meals providing about 917 calories per day for 5 consecutive days, then eat normally for 10 days, and repeat this pattern throughout the study. You will have visits with the research team to check your progress, have blood tests, and provide stool samples so researchers can study how the diet affects your gut bacteria and liver fat. The study is expected to run until May 2026.

AI-generated summary from trial data · Jun 12, 2026 · Not medical advice

Trial locations(3 sites)

China

Physical Examination Center of Gezhouba central hospital of Sinopharm, Yichang, Hubei

Hunan Shanshui physical examination center, Changsha, Hunan

Jinheyuan Outpatient Department, National Sub-health Intervention Technology Achievement Application Center, Changsha, Hunan