Plain-English translation of NCT07083492 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The PICCOLINO trial is studying a new, non-invasive device that can detect iron deficiency in pregnant women by measuring a substance called zinc protoporphyrin at the lower lip. Researchers will compare this quick scan with traditional blood tests to see if it's an accurate and practical way to screen for low iron during pregnancy. The goal is to find a simpler alternative to blood draws that could help doctors identify iron deficiency earlier and prevent serious complications for mothers and babies.
Iron deficiency is very common during pregnancy and can cause maternal fatigue, increased need for blood transfusion during delivery, and problems for the newborn. Current screening methods using blood tests are inconsistent and sometimes unreliable, so doctors need a better, faster, and less invasive way to identify pregnant women with low iron.
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You will visit the study team at five different times: once during each trimester of pregnancy, at the time of delivery, and about 2–3 months after delivery. At each visit, a simple scan will be performed on your lower lip using an optical sensor (no needles), and blood samples will be taken during routine care if possible. You will also complete brief questionnaires about your health, mood, sleep quality, and nutrition to help researchers understand how iron levels affect your overall well-being.
AI-generated summary from trial data · Jul 5, 2026 · Not medical advice
Germany
Sponsor
Wuerzburg University Hospital
Enrollment target
~500 participants
Started
November 2022
Primary completion
December 2026
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in July 2025.
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Central contact
Peter Kranke, MD, MBA
Wuerzburg University Hospital
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