Recruiting

Testing a new implant for severe emphysema and COPD

Plain-English translation of NCT07086339 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated July 2026 · How we translate trials

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This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a new device called the Implantable Artificial Bronchus 50 Flex (IAB 50 Flex) for people with severe emphysema or COPD. The device is surgically placed in the lungs to help improve breathing and reduce symptoms. Researchers want to see if this treatment is safe and whether it helps patients breathe better and feel less short of breath.

Severe emphysema damages the lungs and makes it very hard to breathe. Current treatments don't work well for everyone, and some patients have few options left. This trial is testing whether this new implant can give people relief when other treatments haven't been enough.

Do you qualify?

You likely qualify if…

you have been diagnosed with severe COPD or emphysema
you are at least 22 years old
you have not smoked (including vaping and marijuana) for at least 4 months before screening
you can walk between 100 and 400 meters in 6 minutes
your lung disease is stable, meaning you're not having frequent flare-ups requiring hospitalization
your body mass index (BMI) is between 18 and 32

You likely don't qualify if…

you have been hospitalized for COPD flare-ups more than twice in the past year
you have had a recent heart attack or unstable heart failure within the past 6 months
you have had previous lung surgery, including lung transplant or other lung volume reduction procedures
you are currently taking blood thinners or anti-platelet medications that cannot be safely stopped
you have uncontrolled high blood pressure in your lungs or evidence of severe heart problems

What participation looks like

If you qualify and enroll, you will undergo one or two procedures to have up to 10 small implants placed in one or both of your lungs. The surgery will be performed at one of two specialized hospitals involved in the trial. After the procedure, you will have follow-up visits to monitor your recovery, check how well the implants are working, and assess whether your breathing and ability to exercise have improved.

AI-generated summary from trial data · Jul 8, 2026 · Not medical advice

Trial locations(2 sites)

France

DUPUYTREN University Hospital, Limoges

Netherlands

University Medical Center Groningen, Groningen