Plain-English translation of NCT07088107 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a closed-loop neurofeedback system that combines two technologies: transcranial magnetic stimulation (TMS), which uses magnetic pulses to stimulate the brain, and functional near-infrared spectroscopy (fNIRS), which measures blood flow in the brain in real time. The system learns each person's brain signals and delivers TMS pulses at the exact moment when the brain is most responsive, with the goal of improving arm movement and strength in stroke survivors.
Current brain stimulation treatments for stroke work inconsistently because they deliver stimulation on a fixed schedule rather than responding to the brain's actual activity. This trial exists to test whether timing the stimulation to match each person's brain signals in real time can make the treatment more effective and help more people recover arm function after stroke.
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Participants will receive sessions of magnetic brain stimulation combined with real-time brain imaging feedback. In one group, the timing of stimulation will be controlled by the live brain imaging system; in the other, it will follow a set schedule. During sessions, you will be asked to imagine moving your affected arm while the system measures your brain's response and delivers magnetic pulses. The trial will test your arm strength and brain activity before, during, and after the treatment to see if the adaptive approach helps recovery.
AI-generated summary from trial data · Jul 22, 2026 · Not medical advice
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