Plain-English translation of NCT07090005 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing two different ways to reduce stomach size without surgery—both performed using a camera inserted through your mouth. The EndoZip System uses an automated tool to create sections in your stomach, while the Apollo Endoscopic Sleeve Gastroplasty uses manual stitching to reshape it. Both approaches are designed to help you feel full faster and eat less, combined with changes to your eating habits and behavior.
Many people struggle to lose weight with diet and exercise alone, and this trial is comparing two newer, less invasive options to traditional weight-loss surgery to see which approach works better and is safest.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll be randomly assigned to receive one of the two endoscopic procedures. The procedure itself involves a camera passed through your mouth to reshape your stomach—no external cuts. You'll then participate in a medically supervised diet and behavior modification program. You'll return for follow-up visits, blood tests, and questionnaires throughout a 12-month period to track your weight loss and any side effects.
AI-generated summary from trial data · Oct 5, 2026 · Not medical advice
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