How a new cystic fibrosis medication affects blood sugar control

Researchers want to understand how a newer cystic fibrosis medication called elexacaftor/tezacaftor/ivacaftor affects blood sugar control in people with both cystic fibrosis and diabetes. To do this, they'll give you a special meal and measure how your body processes the glucose (sugar) in it, looking at your insulin levels and how your cells respond to insulin. The study compares how this medication works in people who can take it versus those who cannot.

Cystic fibrosis can damage the pancreas and lead to diabetes, and doctors are not yet sure whether this newer medication helps improve blood sugar control. This study will gather early evidence to understand whether this treatment can help protect pancreas function in people with both conditions.