Testing a psychedelic medication with therapy support for trauma

This research study is testing psilocybin — a psychedelic compound — as a potential new treatment for people with post-traumatic stress disorder (PTSD) and depression. Researchers want to understand how this medication works in the brain and whether combining it with mindfulness-based therapy helps more than support alone. About 30 people with moderate to severe PTSD will participate in this small pilot study.

Many people with PTSD don't respond well enough to medications and therapies that are currently available. Scientists are exploring whether this medication might offer hope to those who have struggled with standard treatments, but they need to understand how it works and what type of psychological support works best alongside it.