Plain-English translation of NCT07107945 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a medication called to see if it can help slow or improve chronic kidney disease in children and teenagers. Researchers want to understand how well this treatment works, how safe it is, and how the young body processes it. Some participants will receive the medication while others receive a placebo (a pill with no medicine) for the first 6 months, then everyone will receive the actual medication for the remaining year.
Chronic kidney disease in children can get worse over time and lead to serious complications. This medication has shown promise in adults, and now researchers need to test whether it is safe and effective for young patients.
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You will be in the study for about 18 months total. During the first 6 months, you will take either the medication or a placebo once daily as a tablet. After that, you will take the actual medication for 1 more year. You will visit the study site about 15 times and receive at least 5 phone or video check-ins from the research team. At visits, they will collect blood and urine samples and monitor your health to watch for any side effects.
AI-generated summary from trial data · Jul 14, 2026 · Not medical advice
United States