Plain-English translation of NCT07107971 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After a heart attack or acute coronary event, many patients have dangerous fatty buildup (plaque) in their coronary arteries that could cause future heart problems. This trial compares two approaches: treating these risky plaques with a special drug-coated balloon (paclitaxel-coated balloon) on top of standard heart medications, versus standard medications alone. The goal is to see whether the balloon treatment can reduce the amount of dangerous plaque and lower the risk of future heart events.
About half of patients who survive a heart attack still have other dangerous plaques lurking in their arteries that could rupture and cause another heart attack. Current standard medications may not be enough to stabilize these risky plaques. This trial is testing whether a targeted local treatment with this medication can reduce these hidden threats and prevent future cardiac events.
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If you join this trial, you will undergo advanced imaging of your heart arteries to identify dangerous plaques. You will then be randomly assigned to either receive a drug-coated balloon treatment of the risky plaque in addition to your standard heart medications, or to continue with standard medications alone. You will have follow-up visits and imaging studies over several months to monitor how your plaques respond to the treatment and to track your heart health.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
Netherlands