Plain-English translation of NCT07108920 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing botulinum toxin injections in the rectus femoris muscle (part of your thigh) to treat stiff knee gait—a walking problem where the knee stays too tense and won't bend properly. Stiff knee gait commonly affects people who have had a stroke, brain injury, or have multiple sclerosis. The research team wants to understand whether this treatment helps you walk better and whether it affects your balance and fall risk.
Muscle stiffness in the legs after stroke or brain injury can severely limit how well someone can walk and move. While this medication is known to relax stiff muscles, doctors need to understand its effects on balance and safety, especially the risk of falls when it is used for this specific leg problem.
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You would receive botulinum toxin injections into your thigh muscle as the study's main treatment. The research team would then assess your walking, balance, and fall risk through physical tests and evaluations before and after the injection. You will be monitored to see how the treatment affects your ability to walk and whether your balance or fall risk changes—helping doctors understand both the benefits and safety of this approach for stiff knee problems.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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