Testing a common allergy medication to prevent nerve damage from breast cancer chemotherapy

This trial is testing whether desloratadine, a medication commonly used for allergies, might prevent or reduce nerve damage in the hands and feet that sometimes happens during breast cancer chemotherapy. Nerve damage from chemotherapy can cause numbness, tingling, and pain that may last long after treatment ends. This study wants to see if taking this medication during your chemotherapy can help protect your nerves.

Nerve damage from chemotherapy is one of the most common side effects that breast cancer patients experience, but currently there are no proven ways to prevent it. Research in animals has shown that this medication might reduce the inflammation in nerves that causes this damage, so doctors want to test whether it works in people.