Plain-English translation of NCT07110376 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is studying how to optimize deep brain stimulation (DBS)—a device already implanted in your brain to help manage Parkinson's symptoms—specifically to improve sleep. Researchers will test three different stimulation settings over 6 weeks while you sleep at home, measuring how each setting affects your sleep quality and brain activity. The goal is to understand which stimulation levels work best for helping people with Parkinson's disease sleep better.
Sleep problems are very common in Parkinson's disease and seriously affect quality of life, but doctors don't yet know the best way to use brain stimulation to help with sleep. This trial aims to fill that gap by studying how different stimulation settings change sleep patterns and brain activity, so future devices can be programmed to automatically adjust and give you better sleep.
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You will wear a special headband that monitors your brain waves while you sleep at home for 6 weeks. During this time, your brain stimulation device will be set to three different levels (no stimulation, reduced stimulation, and your normal clinical setting) for 2 weeks each, in random order. One night during the study, you'll come in for an overnight sleep test to confirm the headband readings are accurate. Researchers will also record the electrical activity from your implanted device to see how brain patterns change with different stimulation settings.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
The Cleveland Clinic
Collaborators
American Parkinson's Disease Association, Inc, Beacon Biosignals
Enrollment target
~10 participants
Started
November 2025
Primary completion
July 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Saar Anis, MD
The Cleveland Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.