Recruiting

Testing AI-Assisted Imaging to Diagnose Crohn Disease

Plain-English translation of NCT07111715 on ClinicalTrials.gov ↗ · Source last updated September 2026 · Translation generated September 2026 · How we translate trials

What is this trial?

This study is testing a new approach to diagnosing Crohn disease using capsule endoscopy — a small camera pill you swallow that takes pictures inside your small intestine. The study will compare how well artificial intelligence can analyze these pictures versus traditional manual review by doctors. If you have symptoms suggesting Crohn disease but your previous colonoscopy was inconclusive or negative, this trial may help confirm whether you actually have the condition.

Crohn disease can be difficult to diagnose because symptoms overlap with other conditions, and sometimes inflammation is missed on standard tests. Artificial intelligence might help doctors spot signs of inflammation more reliably, leading to faster and more accurate diagnoses for patients who need treatment.

Do you qualify?

You likely qualify if…

you are between 18 and 75 years old
you have symptoms suggesting Crohn disease, such as chronic diarrhea, abdominal pain, or weight loss
you have had a colonoscopy that either showed nothing abnormal or showed unclear inflammatory changes that don't clearly indicate Crohn disease
you have been tested to rule out infections in your digestive system
you have confirmed normal small bowel function (ability to pass a patency capsule without blockage)

You likely don't qualify if…

you have already been diagnosed with Crohn disease
you have been diagnosed with ulcerative colitis, diverticular disease, colorectal cancer, or other serious bowel conditions
you have had a recent positive test for bacterial, parasitic, or C. difficile infections in your stool
you are currently taking NSAIDs (non-steroidal anti-inflammatory drugs like ibuprofen) or have taken them in the past 4 weeks
you have severe kidney disease, swallowing problems, or conditions that affect how your stomach empties

What participation looks like

At a screening visit, you'll complete questionnaires about how your symptoms affect your quality of life, mood, and energy levels. If you meet all requirements, you'll swallow a small camera capsule that travels naturally through your small intestine over 8–10 hours, taking thousands of pictures. Some patients may first swallow a patency capsule to confirm there are no blockages. The capsule eventually passes through your system naturally. Doctors will review the images using both traditional manual reading and artificial intelligence analysis to look for signs of Crohn disease.

AI-generated summary from trial data · Sep 5, 2026 · Not medical advice

Testing AI-Assisted Imaging to Diagnose Crohn Disease

What is this trial?

Do you qualify?

What participation looks like

Trial locations