Plain-English translation of NCT07112690 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a procedure called ganglion impar neurolysis to help manage severe pain during radiation and chemotherapy treatment for anal cancer. The procedure works by blocking pain signals from nerves in the lower abdomen. Researchers want to see if this treatment can help patients stay on track with their cancer therapy by reducing pain-related treatment breaks.
Radiation and chemotherapy for anal cancer can cause intense pain that sometimes forces patients to pause or skip treatments, which can affect how well the cancer therapy works. This trial exists to find out if this nerve-blocking procedure can control that pain and help patients complete their full cancer treatment.
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If you join this study, you will receive the nerve-blocking procedure during the 4th week of your radiation therapy. The procedure uses imaging guidance to help the doctor locate and treat the specific nerves causing your pain. After the procedure, you will be followed during your final week of radiation therapy and again at 3–6 months after treatment ends. You'll also complete questionnaires about your pain levels and any side effects.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States